Epidemiological insights into colorectal cancer in northwestern Algeria

Journal article

El Herrag Salah Eddine, Moulessehoul Soraya, El Mehadji Douniazad, Yekrou Djamila, Khaled Méghit Boumediène
ecancermedicalscience, vol. 18, 2024 Mar, p. 1684

DOI: 10.3332/ecancer.2024.1684

Cite

APA Click to copy
Salah Eddine, E. H., Soraya, M., Douniazad, E. M., Djamila, Y., & Méghit Boumediène, K. (2024). Epidemiological insights into colorectal cancer in northwestern Algeria. Ecancermedicalscience, 18, 1684. https://doi.org/10.3332/ecancer.2024.1684

Chicago/Turabian Click to copy
Salah Eddine, El Herrag, Moulessehoul Soraya, El Mehadji Douniazad, Yekrou Djamila, and Khaled Méghit Boumediène. “Epidemiological Insights into Colorectal Cancer in Northwestern Algeria.” ecancermedicalscience 18 (March 2024): 1684.

MLA Click to copy
Salah Eddine, El Herrag, et al. “Epidemiological Insights into Colorectal Cancer in Northwestern Algeria.” Ecancermedicalscience, vol. 18, Mar. 2024, p. 1684, doi:10.3332/ecancer.2024.1684.

BibTeX Click to copy

@article{salah2024a,
  title = {Epidemiological insights into colorectal cancer in northwestern Algeria},
  year = {2024},
  month = mar,
  journal = {ecancermedicalscience},
  pages = {1684},
  volume = {18},
  doi = {10.3332/ecancer.2024.1684},
  author = {Salah Eddine, El Herrag and Soraya, Moulessehoul and Douniazad, El Mehadji and Djamila, Yekrou and Méghit Boumediène, Khaled},
  month_numeric = {3}
}

Abstract

Objectives: The incidence of colorectal cancer (CRC) has exhibited regional variability in North Africa and the Middle East, with a steady increase in Algeria. Despite this trend, limited data exist on the epidemiology of CRC in northwestern Algeria. Our study aimed to investigate the epidemiological characteristics of CRC in this region.

Methods: We conducted a retrospective study examining 255 confirmed CRC cases through medical records from patients at the Sidi Bel Abbes anti-cancer centre.

Results: The mean age of the study participants was 59 ± 13 years. The results showed a higher incidence in males (57%) than in females, and colon (62%) than rectal cancer. Within this cohort, 47% had a pre-existing medical condition, while 39% had a family history of cancer. Adenocarcinomas were the prevailing histological subtype in 94% of CRC cases. Compared with colon cancer, rectal cancer was less often diagnosed at stage IV of the disease (OR = 0.75; 95% CI = 0.09, 4.86; p = 0.8) and more likely in early-onset patients (OR = 2.27; 95% CI = 1.25, 4.17; p = 0.007). Men were at a higher risk of being diagnosed with metastatic CRC primarily hepatic metastases (OR = 2.03; 95% CI = 1.07, 3.99; p = 0.033) and pulmonary metastases (OR = 2.50; 95% CI = 1.07, 6.59; p = 0.045).

Conclusion: This study may provide a comprehensive glimpse into CRC epidemiology in northwest Algeria. Understanding regional differences is the key to implementing specific preventive and interventional strategies.

Keywords: colorectal neoplasms, epidemiology, incidence, Algeria